Lorién López-Villellas
PhD Student in High Performance Computing
Computer Architecture group of Zaragoza (gaZ), University of Zaragoza
High-Performance Algorithms and Hardware Accelerators for Bioinformatics (HPCBio), Barcelona Supercomputing Center
I work on accelerating bioinformatics and molecular dynamics through hardware-aware algorithms, data structures, and performance-critical implementations. My experience includes parallelization, vectorization, and performance engineering, with a strong focus on how algorithms interact with and exploit modern computer architectures. I enjoy bridging the gap between algorithm design and computer architecture to deliver faster and more efficient scientific applications.
Publications
Singletrack: An Algorithm for Improving Memory Consumption and Performance of Gap-Affine Sequence Alignment
[bioRXiv]
Lorién López-Villellas, Cristian Iñiguez, Albert Jiménez-Blanco, Quim Aguado-Puig, Miquel Moretó, Jesús Alastruey-Benedé, Pablo Ibáñez, Santiago Marco-Sola
bioRXiv. Published online, October 2025.
How Accurate is Richardson's Error Estimate?
[Wiley]
Carl Christian Kjelgaard Mikkelsen and Lorién López-Villellas
Concurrency And Computation: Practice And Experience. Published online, November 2025.
ILVES: Accurate and efficient bond length and angle constraints in molecular dynamics
[ACS Publications] [Code (GitHub)]
Lorién López-Villellas, Carl Christian Kjelgaard Mikkelsen, Juan José Galano-Frutos, Santiago Marco-Sola, Jesús Alastruey-Benedé, Pablo Ibáñez, Miquel Moretó, Maria Cristina De Rosa, and Pablo García-Risueño
Journal of Chemical Theory and Computation. Published online, September 2025.
Improving detection and figures of merit in single-particle inductively coupled plasma-mass spectrometry via transient event heights
Antonio Bazo, Lorién López-Villellas, Matilde Mataloni, Eduardo Bolea-Fernandez, Ana Rua-Ibarz, Marco Grotti, Maite Aramendía and Martín Resano
Analytica Chimica Acta. Published online, September 2025.
The need for accuracy and smoothness in numerical simulations
[Springer]
Carl Christian Kjelgaard Mikkelsen and Lorién López-Villellas
Parallel Processing and Applied Mathematics - 15th International Conference (PPAM 2024), Ostrava, Czech Republic, September 8-11, 2024. It appears in Springer's LNCS vol. 15579.
RISC-V for Genome Data Analysis: Opportunities and Challenges
[IEEE] [PDF] [Code (GitHub)]
Lorién López-Villellas, Esteve Pineda-Sánchez, Asaf Badouh, Santiago Marco-Sola, Pablo Ibáñez, Jesús Alastruey-Benedé, and Miquel Moretó
Proceedings of the XXXVIII Conference on Design of Circuits and Integrated Systems (DCIS 2023), Málaga, Spain, 2023, pp. 1-6.
GenArchBench: A Genomics Benchmark Suite for Arm HPC Processors
[ScienceDirect] [PDF] [Code]
Lorién López-Villellas, Rubén Langarita-Benítez, Asaf Badouh, Víctor Soria-Pardos, Quim Aguado-Puig, Guillem López-Paradís, Max Doblas, Javier Setoain, Chulho Kim, Makoto Ono, Adrià Armejach, Santiago Marco-Sola, Jesús Alastruey-Benedé, Pablo Ibáñez, Miquel Moretó
Future Generation Computer Systems. Published online, April 2024.
Newton's method revisited: How accurate do we have to be?
[Wiley] [PDF] [Code (GitHub)]
Carl Christian Kjelgaard Mikkelsen, Lorién López-Villellas and Pablo García-Risueño
Concurrency And Computation: Practice And Experience. Published online, July 2023.
Accurate and efficient constrained molecular dynamics of polymers using Newton's method and special purpose code
[ScienceDirect] [PDF] [Code (GitHub)]
Lorién López-Villellas, Carl Christian Kjelgaard Mikkelsen, Juan José Galano-Frutos, Santiago Marco-Sola, Jesús Alastruey-Benedé, Pablo Ibáñez, Miquel Moretó, Javier Sancho, and Pablo García-Risueño
Computer Physics Communications. Volume 288, July 2023.
How Accurate Does Newton Have to Be?
Carl Christian Kjelgaard Mikkelsen, Lorién López-Villellas and Pablo García-Risueño
Parallel Processing and Applied Mathematics - 14th International Conference (PPAM 2022), Gdansk, Poland, September 11-14, 2022. It appears in Springer's LNCS vol. 13826.